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Patients should never ignore significant changes in how they feel after treatment

Neutrophil extracellular traps in systemic lupus erythematosus: Pathogenic mechanisms, crosstalk with oxidative stress, and antioxidant therapeutic potential

When to be cautious: If you have Hashimotos (check TPO antibodies first)-high-dose iodine can worsen autoimmunity If youre on thyroid medication-can interfere with dosing 2

In summary, in SLE patients, mtROS accumulation and mtDNA release may promote ferroptosis and subsequent release of intracellular antigens and DAMPs, thereby mediating the progression of SLE ( Figure 2 )

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